| Document ID (ISN) | 100896 |
| CIS number |
02-1803 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2002 |
| Convention or series no. |
|
| Author(s) |
Peiris-John R.J., Ruberu D.K., Wickremasinghe A.R., Smit L.A.M., van der Hoek W. |
| Title |
Effects of occupational exposure to organophosphate pesticides on nerve and muscular function |
| Bibliographic information |
Apr. 2002, Vol.44, No.4, p.352-357. Illus. 17 ref. |
| Abstract |
This study aimed to investigate whether occupational exposure to organophosphate (OP) pesticides caused neurophysiological abnormalities. 30 farmers who regularly spray OP pesticides and 30 fishermen (controls), living close by, were evaluated during and between cultivation seasons. The farmers had higher erythrocyte acetylcholinesterase levels than the controls during and between cultivation seasons. During the cultivation season, there was a significant reduction in erythrocyte acetylcholinesterase activity in both groups. Significant differences between the farmers and controls were found in sensory conduction velocity and motor conduction velocity between cultivation seasons. Sensory conduction velocity was reduced significantly in farmers and in controls during the cultivation season. Effects of OP poisoning were seen both in farmers and in controls who had no history of spray activities. Evidence of sensory dysfunction after acute exposure and sensory and motor impairment after long-term low-level exposure to OP was observed. |
| Descriptors (primary) |
neurotoxic effects; organophosphorus compounds; agriculture; neuromuscular disorders; pesticides |
| Descriptors (secondary) |
poisoning; pesticide poisoning; nervous function tests; acetylcholinesterase; pesticide spraying; case-control study; nervous conduction; short-term exposure; long-term exposure; Sri Lanka |
| Document type |
D - Periodical articles |
| Country / State or Province | Sri Lanka |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agricultural chemicals
Diseases of the nervous system
Agriculture
|
