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CISDOC database

Document ID (ISN)100767
CIS number 02-1686
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2002
Convention or series no.
Author(s) Zanoni G., Martini S., Zedde A., Pagani M., Guarnieri A., Tridente G., Romeo L.
Title Specific immune response to occupational antigens in asymptomatic egg processing workers
Bibliographic information June 2002, Vol.41, No.6, p.490-497. 24 ref.
Abstract Hen's egg proteins are known sensitizers and may cause occupational respiratory diseases in exposed workers. This study was conducted in order to determine the prevalence of sensitization to work-related antigens in asymptomatic egg processing factory workers. Clinical history, respiratory function, atopy and the presence of specific antibodies to environmental and occupational antigens were evaluated in 77 workers. A total of 116 unexposed controls were also studied. The antigen concentration of the factory environment was measured. Specific IgE and precipitin positivity to egg components was more frequently present in workers than among controls. The egg white protein concentration was higher in the egg breaking area. The avian proteins inhaled induced immune responses to occupational antigens in asymptomatic, professionally exposed subjects. Measures to decrease environmental antigen concentrations and thorough monitoring of sensitized workers are advocated.
Descriptors (primary) eggs; proteins; sensitization; food industry; allergic respiratory disorders; biological hazards
Descriptors (secondary) immunoglobulins; antigens; antibodies; medical supervision; individual susceptibility; determination in air; determination in blood; case-control study
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Food, beverage and tobacco industries
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Food industry
Biological hazards