|Document ID (ISN)||100767|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Zanoni G., Martini S., Zedde A., Pagani M., Guarnieri A., Tridente G., Romeo L.
||Specific immune response to occupational antigens in asymptomatic egg processing workers
||June 2002, Vol.41, No.6, p.490-497. 24 ref.
||Hen's egg proteins are known sensitizers and may cause occupational respiratory diseases in exposed workers. This study was conducted in order to determine the prevalence of sensitization to work-related antigens in asymptomatic egg processing factory workers. Clinical history, respiratory function, atopy and the presence of specific antibodies to environmental and occupational antigens were evaluated in 77 workers. A total of 116 unexposed controls were also studied. The antigen concentration of the factory environment was measured. Specific IgE and precipitin positivity to egg components was more frequently present in workers than among controls. The egg white protein concentration was higher in the egg breaking area. The avian proteins inhaled induced immune responses to occupational antigens in asymptomatic, professionally exposed subjects. Measures to decrease environmental antigen concentrations and thorough monitoring of sensitized workers are advocated.
||eggs; proteins; sensitization; food industry; allergic respiratory disorders; biological hazards
||immunoglobulins; antigens; antibodies; medical supervision; individual susceptibility; determination in air; determination in blood; case-control study
||D - Periodical articles
|Country / State or Province||Italy|
||Food, beverage and tobacco industries
|Broad subject area(s)
||Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)