|Document ID (ISN)||100528|
|Convention or series no.
||Toxikologische Bewertung Nr.78
||4-Chlorphenylisocyanat [in German]|
||Berufsgenossenschaft der chemischen Industrie, Postfach 10 14 80, 69004 Heidelberg, Germany, Jan. 1997. 23p. 20 ref.
||Repeated contact with 4-chlorophenyl isocyanate causes itchy erythema and dryness of the skin. The substance irritates the eyes. Animal experiments show high toxicity upon inhalation exposure and harmful to toxic effects upon acute oral and dermal administration. No genotoxic effect has been observed. A comparison of the toxic effects of 4-chlorophenyl isocyanate, phenyl isocyanate and 4-isopropylphenyl isocyanate in humans and animals is also presented. In humans, the only toxic effect described is an itchy erythema after repeated contact with chlorophenyl isocyanate.
||4-chlorophenyl isocyanate; Germany; pharmaceutical industry; pesticides; toxicity evaluation; isocyanates
||toxic effects; literature survey; criteria document; erythema; animal experiments; irritants
||B - Chemical safety information sheets
|Country / State or Province||Germany|
||Toxic and dangerous substances
|Broad subject area(s)