|Document ID (ISN)||100384|
|ISSN - Serial title
||0007-9952 - Cahiers de notes documentaires - Hygiène et sécurité du travail
|Convention or series no.
||INRS ND 2133-180-00
||Moulin J.J., Clavel T., Roy D., Dananché B., Marquis N., Févotte J., Fontana J.M.
||Risk of bronchopulmonary cancer in a stainless and alloyed steels plant
||Risques de cancers bronchopulmonaires dans une usine sidérurgique produisant des aciers inoxydables et des aciers alliés [in French]|
||3rd Quarter 2000, No.180, p.49-59. 49 ref.
||The mortality of workers involved in the production of stainless and alloyed steel in France from 1968 to 1992 was studied. The study design was a historical cohort mortality study and a nested case-control study concerning lung cancer. Relative risk was expressed in the form of standardized mortality ratios (SMRs). Conditional logistic regression was used to estimate odds ratios (ORs). The cohort comprised 4,288 male and 609 female workers. The observed overall mortality was significantly lower than expected (649 deaths; SMR = 0.91). No significant SMR was observed for mortality from bronchopulmonary cancer (54 deaths; SMR = 1.19). The case-control study was based on 54 cases and 162 individually matched controls. No bronchopulmonary cancer excess was observed for exposure to iron (OR = 0.94), chromium and/or nickel (OR = 1.18), cobalt (OR = 0.64), acid mists (OR = 0.43) and asbestos (OR = 1.00). However, high and statistically significant bronchopulmonary cancer excesses were observed for exposure to polycyclic aromatic hydrocarbons (PAHs) and silica which are often found together in workplaces, the ORs being 1.95 and 2.47 respectively.
||mortality; ferrous alloys; steelworks; lung cancer; bronchial cancer
||iron; chromium; nickel; France; aromatic hydrocarbons; silica; acids; asbestos; steels; stainless steel; aerosols; polycyclic hydrocarbons; case-control study; cohort study; cobalt
||D - Periodical articles
|Country / State or Province||France|
||Metal production and metalworking
|Broad subject area(s)
||Occupational medicine, epidemiology
||Iron and steel industry
Diseases of the respiratory system (except for pneumoconiosis & similar)