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Document ID (ISN)100366
CIS number 02-1344
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2001
Convention or series no.
Author(s) Castillo L., Baldwin M., Sassine M.P., Mergler D.
Title Cumulative exposure to styrene and visual functions
Bibliographic information Apr. 2001, Vol.39, No.4, p.351-360. Illus. 28 ref.
Abstract A 1990-1992 longitudinal study of several reinforced plastics plants had showed that for those workers whose styrene exposure had decreased, colour vision (CV) improved while near-visual contrast sensitivity (CS) was poorer. In 1999, these visual functions were re-tested in 18 workers with good visual acuity. A cumulative exposure index (CEI), corrected for respirator use, was calculated for each worker. For CV, no significant difference was observed between 1992 and 1999. The CS profile decreased over time, with significant differences at frequencies of 3 cycles per degree. CS did not vary with urinary mandelic acid levels, but was significantly depressed at the intermediate frequencies among those in the upper CEI category. These findings suggest that CS loss increases with long-term cumulative exposure, reflecting chronic damage to the neuro-optic pathways.
Descriptors (primary) visual function disorders; vision tests; reinforced plastics; styrene
Descriptors (secondary) atrophy of the optic nerve; mandelic acid; colour vision; determination in urine; visual acuity; respirators; long-term exposure; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceCanada
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic hydrocarbons
Diseases of the eye and vision damage