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Document ID (ISN)100364
CIS number 02-1343
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2000
Convention or series no.
Author(s) van Kampen V., Merget R., Baur X.
Title Occupational airway sensitizers: A review on the respective literature
Bibliographic information Aug. 2000, Vol.38, No.2, p.164-218. 292 ref.
Abstract This article consists of a literature review on the topic of allergic occupational asthma. Papers were selected according to criteria of study design and diagnostic test methods. Approximately 300 publications were reviewed including both epidemiological studies and individual case reports. Technical directives on hazardous substances are enforced in several countries and are being continuously updated; in particular, the European Union has established a code for several occupational substances, now labelled R 42 ("may cause sensitization by inhalation"). The most common sensitizing substances causing occupational asthma were dust of cereal flours, enzymes, natural rubber latex, laboratory animals as well as low molecular substances such as isocyanates and acid anhydrides. A table which lists threshold limit values (TLV), R 42 labelling requirements and a summary of clinical data for 250 airway-sensitizing substances is included.
Descriptors (primary) allergens; irritants; sensitizers; allergic asthma; occupational diseases
Descriptors (secondary) literature survey; classification; European Communities; carboxylic acid anhydrides; enzymes; isocyanates; experimental animals; latex; symptoms; grain dust; diagnosis; labelling; list of chemical substances; skin tests; threshold limit values
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Allergies
Diseases of the respiratory system (except for pneumoconiosis & similar)