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Document ID (ISN)100356
CIS number 02-1342
ISSN - Serial title 0019-8366 - Industrial Health
Year 2001
Convention or series no.
Author(s) Yamano Y., Kagawa J., Ishizu S., Harayama O.
Title Three cases of acute methyl bromide poisoning in a seedling farm family
Bibliographic information Oct. 2001, Vol.39, No.4, p.353-358. Illus. 20 ref.
Abstract Three patients of a same Japanese farming family (39-year-old man, 34-year-old woman, 5-year-old girl) exhibited almost the same initial symptoms, i.e., severe vomiting, tonic convulsions and clouding of consciousness. Subsequent inquiry revealed that 27 cans of methyl bromide had been stored in the building that the patients lived in, and that the cans had been damaged a few days before the onset of the patients' illness. Inspection revealed that all the cans of methyl bromide had passed the expiry date and were corroded. Even though none of the cans had been used, three cans with a capacity of 750g were found to be empty. Plasma bromide ion concentrations were found to be high (72.9µg/mL, 67.8µg/mL and 91.5µg/mL; normal level <5µg/mL), and acute methyl bromide poisoning was diagnosed 8 days after admission of the patients to the hospital. Haemodialysis (peritoneal lavage in the case of the child) was performed immediately, after which the plasma bromide ion concentrations returned to normal and the general condition of the patients gradually improved.
Descriptors (primary) agricultural chemicals; agriculture; methyl bromide; poisoning
Descriptors (secondary) Japan; corrosion; case study; symptoms; methyl benzenesulfonate; exposure evaluation; leakage; neurological effects; determination in blood; cans
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals
Halogenated hydrocarbons