|Document ID (ISN)||100355|
|ISSN - Serial title
||0019-8366 - Industrial Health
|Convention or series no.
||Yokota K., Johyama Y., Miyaue H., Matsumoto N., Yamaguchi K.
||Occupational contact urticaria caused by airborne methyhexahydrophthalic anhydride
||Oct. 2001, Vol.39, No.4, p.347-352. Illus. 20 ref.
||Three subjects with occupational exposure to methyl hexahydrophthalic anhydride (MHHPA) and hexahydrophthalic anhydride (HHPA) from an epoxy resin system were studied to evaluate the nature of their reported skin and nose complaints. Specific IgE antibody was detected in serum from one of the three workers. One unsensitized worker displayed nasal pain and rhinorrhoea only when loading liquid epoxy resins into the pouring machine, probably as a result of an irritant reaction. Two workers had work-related symptoms at relatively low levels of exposure; one complained of only rhinitis, and the other was sensitized against HHPA and displayed both rhinitis and contact urticaria (in the face and neck). The worker's skin symptoms were evidently due to airborne contact, since she had not had any skin contact with liquid epoxy resin or mixtures of MHHPA and HHPA. These urticaria symptoms were confirmed by a 20-min closed patch test for MHHPA, but not by that for HHPA. The causative agent was considered to be MHHPA, although the specific IgE determination to MHHPA was not performed.
||irritants; urticaria; methyl hexahydrophthalic anhydride; epoxy resins
||subjective assessment; immunoglobulins; rhinitis; case study; sensitization; exposure evaluation; skin tests; determination in blood; serological reactions; grotan
||D - Periodical articles
|Country / State or Province||Japan|
|Broad subject area(s)