|Document ID (ISN)||100182|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Meredith S.K., Bugler J., Clark R.L.
||Isocyanate exposure and occupational asthma: A case-referent study
||Dec. 2000, Vol.57, No.12, p.830-836. 25 ref.
||Case study of 34 workers from two British manufacturing companies. In one plant occupational asthma was mainly attributed to tolylene diisocyanate exposure, while in the other one to 4,4'-diphenylmethane diisocyanate. No difference in peak exposures between cases and referents was found in either plant. However, time weighted average (TWA) exposures at the time of onset of asthma were higher for cases. The findings were that asthma can occur at low concentrations of isocyanates, but even then the higher the exposure, the greater the risk. Smoking and atopy seemed to increase the odds of this occupational asthma due to isocyanates.
||diphenylmethane diisocyanate; asthma; tolylene diisocyanate; isocyanates
||United Kingdom; smoking; individual susceptibility; case-control study; exposure evaluation
||D - Periodical articles
|Country / State or Province||United Kingdom|
||Toxic and dangerous substances
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)