|Document ID (ISN)||100019|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Zheng T., Zahm S.H., Cantor K.P., Weisenburger D.D., Zhang Y., Blair A.
||Agricultural exposure to carbamate pesticides and risk of non-Hodgkin lymphoma
||July 2001, Vol.43, No.7, p.641-649. 33 ref.
||To explore the possible relationship between non-Hodgkin lymphoma (NHL) and carbamate insecticide use among farmers, a pooled analysis of three population-based case-control studies conducted in four mid-western states in the United States was conducted involving 985 white male subjects and 2895 matched controls. Compared with non-farmers, farmers who had ever used carbamate pesticides had a 30% to 50% increased risk of NHL, whereas farmers without carbamate pesticide use showed no increased risk. Analyses for individual carbamate pesticides found a more consistent association with Sevin but not carbofuran, butylate, or S-ethyl dipropylthiocarbamate plus protectant. Among farmers using Sevin, the risk of NHL was limited to those who personally handled the product, those who first used the product for >20 years before their disease diagnosis, and those who used the product for a longer period. These associations persisted after adjusting for other major classes of pesticides. These results suggest an increased risk of NHL associated with carbamate pesticide use, particularly Sevin. Further investigation of the association is warranted.
||carbamates; lymphoma; agriculture; long-term exposure; pesticides
||USA; carbofuran; butylate; EPTC; carbaryl; exposure evaluation; case-control study; job-exposure relation; hazard evaluation
||D - Periodical articles
|Country / State or Province||USA|
|Broad subject area(s)