Vol. 1 - Pages 9.1-9.30 (Printed Version) - Tabl* 9.2
Reproductive System
MALE REPRODUCTIVE SYSTEM AND
TOXICOLOGY
Epidemiological studies of paternal effects on pregnancy outcome
|
Reference |
Type of exposure or occupation |
Association with exposure1 |
Effect |
|
Record-based population studies |
|||
|
Lindbohm et al. 1984 |
Solvents |
– |
Spontaneous abortion |
|
Lindbohm et al. 1984 |
Service station |
+ |
Spontaneous abortion |
|
Daniell and Vaughan 1988 |
Organic solvents |
– |
Spontaneous abortion |
|
McDonald et al. 1989 |
Mechanics |
+ |
Spontaneous abortion |
|
McDonald et al. 1989 |
Food processing |
+ |
Developmental defects |
|
Lindbohm et al. 1991a |
Ethylene oxide |
+ |
Spontaneous abortion |
|
Lindbohm et al. 1991a |
Petroleum refinery |
+ |
Spontaneous abortion |
|
Lindbohm et al. 1991a |
Impregnants of wood |
+ |
Spontaneous abortion |
|
Lindbohm et al. 1991a |
Rubber chemicals |
+ |
Spontaneous abortion |
|
Olsen et al. 1991 |
Metals |
+ |
Child cancer risk |
|
Olsen et al. 1991 |
Machinists |
+ |
Child cancer risk |
|
Olsen et al. 1991 |
Smiths |
+ |
Child cancer risk |
|
Kristensen et al. 1993 |
Solvents |
+ |
Preterm birth |
|
Kristensen et al. 1993 |
Lead and solvents |
+ |
Preterm birth |
|
Kristensen et al. 1993 |
Lead |
+ |
Perinatal death |
|
Kristensen et al. 1993 |
Lead |
+ |
Male child morbidity |
|
Case-control studies |
|||
|
Kucera 1968 |
Printing industry |
(+) |
Cleft lip |
|
Kucera 1968 |
Paint |
(+) |
Cleft palate |
|
Olsen 1983 |
Paint |
+ |
Damage to central nervous system |
|
Olsen 1983 |
Solvents |
(+) |
Damage to central nervous system |
|
Sever et al. 1988 |
Low-level radiation |
+ |
Neural tube defects |
|
Taskinen et al. 1989 |
Organic solvents |
+ |
Spontaneous abortion |
|
Taskinen et al. 1989 |
Aromatic hydrocarbons |
+ |
Spontaneous abortion |
|
Taskinen et al. 1989 |
Dust |
+ |
Spontaneous abortion |
|
Gardner et al. 1990 |
Radiation |
+ |
Childhood leukaemia |
|
Bonde 1992 |
Welding |
+ |
Time to conception |
|
Wilkins and Sinks 1990 |
Agriculture |
(+) |
Child brain tumour |
|
Wilkins and Sinks 1990 |
Construction |
(+) |
Child brain tumour |
|
Wilkins and Sinks 1990 |
Food/tobacco processing |
(+) |
Child brain tumour |
|
Wilkins and Sinks 1990 |
Metal |
+ |
Child brain tumour |
|
Lindbohmn et al. 1991b |
Lead |
(+) |
Spontaneous abortion |
|
Sallmen et al. 1992 |
Lead |
(+) |
Congenital defects |
|
Veulemans et al. 1993 |
Ethylene glycol ether |
+ |
Abnormal spermiogram |
|
Chia et al. 1992 |
Metals |
+ |
Cadmium in semen |
1 – no
significant association; (+) marginally significant association; + significant
association.
Source: Adapted from Taskinen 1993.