ICSC 1651 - ISOBUTYL NITRITE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

ISOBUTYL NITRITE

ICSC: 1651
_{April 2006}

Nitrous acid, 2-methylpropyl ester
Nitrous acid, isobutyl ester

CAS No: 542-56-3
RTECS No: RA0805000
UN No: 1992
EC No: 007-017-00-2

C₄H₉NO₂ / (CH₃)₂CHCH₂NO₂
Molecular mass: 103.1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames, NO sparks, and NO smoking.	Dry powder. Carbon dioxide.
EXPLOSION	Vapour/air mixtures are explosive.	Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE		AVOID ALL CONTACT!
Inhalation	Sore throat. Headache. Dizziness. Blue lips or finger nails. Blue skin. Nausea. Confusion. Convulsions. Unconsciousness. Symptoms may be delayed (see Notes).	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin		Protective gloves. Protective clothing.	Rinse and then wash skin with water and soap.
Eyes		Safety spectacles.	Rinse with plenty of water (remove contact lenses if easily possible).
Ingestion	(See Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Evacuate danger area! Consult an expert! Ventilation. Remove all ignition sources. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer.	EU classification F Symbol Xn Symbol R: 11-20/22-45-68 S: 53-45 UN classification UN Hazard Class: 3 UN Subsidiary Risks: 6.1 UN Pack Group: III GHS classification Signal: Danger Flame-Skull-Health haz Highly flammable liquid and vapour Harmful if swallowed Toxic if inhaled vapour Suspected of causing cancer Causes damage to blood	Do not transport with food and feedstuffs.

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-30GTF1-III	Fireproof. Separated from acids. Well closed.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS LIQUID.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
The substance decomposes on burning producing toxic gases including nitrogen oxides.

Occupational exposure limits
TLV: (Ceiling value) 1 ppm, A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued (ACGIH 2006).
MAK not established.

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of short-term exposure
The substance may cause effects on the blood and cardiovascular system resulting in cardiac disorders and the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. Exposure at high levels may result in death. See Notes.

Effects of long-term or repeated exposure
This substance is possibly carcinogenic to humans.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Boiling point: 67°C Relative density (water = 1): 0.87 Solubility in water: very poor Vapour pressure, kPa at 20°C: 1.3 Relative vapour density (air = 1): 3.56 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.19 Flash point: -21°C Explosive limits, vol% in air: 1.2 - 26.9

NOTES

Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2006

LEGAL NOTICE

Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

Updated by AS. Approved by GS. Last update: 29.01.2008