ICSC 1633 - 1-CHLORO-3-NITROBENZENE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

1-CHLORO-3-NITROBENZENE

ICSC: 1633
_{April 2007}

Benzene, 1-chloro-3-nitro-
m-Chloronitrobenzene

CAS No: 121-73-3
RTECS No: CZ0940000
UN No: 1578

ClC₆H₄NO₂
Molecular mass: 157.6

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Water spray, foam, carbon dioxide.
EXPLOSION	Finely dispersed particles form explosive mixtures in air.

EXPOSURE		PREVENT DISPERSION OF DUST! STRICT HYGIENE!
Inhalation	Blue lips or finger nails. Dizziness. Headache. Nausea. Confusion. Convulsions.	Local exhaust. Breathing protection.	Fresh air, rest. Refer for medical attention. See Notes.
Skin	MAY BE ABSORBED! (see Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell
Eyes	Redness.	Safety goggles.	Rinse with plenty of water (remove contact lenses if easily possible).
Ingestion	Blue skin. (See Inhalation).	Do not eat, drink, or smoke during work.	Rinse mouth. Refer immediately for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into sealablecontainers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.	UN classification UN Hazard Class: 6.1 UN Pack Group: II GHS classification Signal: Danger Skull-Health haz Harmful if swallowed Toxic in contact with skin Toxic to aquatic life Causes damage to blood	Do not transport with food and feedstuffs.

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-II and 61S1578 NFPA Code: H2; F1; R; 0	Separated from combustible and reducing substances, food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.

IMPORTANT DATA

Physical State; Appearance
PALE-YELLOW CRYSTALS, WITH CHARACTERISTIC ODOUR.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides, chlorine (See ICSC 0126), hydrogen chloride (See ICSC 0163), and phosgene (See ICSC 0007), causing fire and explosion hazard. The substance is a strong oxidant and reacts with combustible and reducing materials.

Occupational exposure limits
TLV not established.
MAK: IIb (not established but data is available) skin absorption (H); (DFG 2006).

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

Effects of short-term exposure
The substance is mildly irritating to the eyes. The substance may cause effects on the blood, resulting in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.

Effects of long-term or repeated exposure
The substance may have effects on the blood, resulting in the formation of methaemoglobin.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Boiling point: 236°C Melting point: 44°C Density: 1.3 g/cm³ Solubility in water, g/100 ml at 20°C: (very poor) Vapour pressure, Pa at 20°C: 5 Relative vapour density (air = 1): 5.44 Flash point: 103°C c.c. Auto-ignition temperature: 500°C Octanol/water partition coefficient as log Pow: 2.41	The substance is toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment.

NOTES

TLV (as para-nitrochlorobenzene): 0.1 ppm (skin) A3 (confirmed animal carcinogen with unknown relevance to humans) BEI issued (ACGIH 2006).
See ICSC0028.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Rinse contaminated clothes with plenty of water because of fire hazard.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2006

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Updated by AS. Approved by GS. Last update: 29.01.2008