ICSC 1086 - METHYLACETOACETATE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

METHYLACETOACETATE

ICSC: 1086
_{November 2003}

Acetoacetic acid methyl ester
Butanoic acid, 3-oxo-, methyl ester
1-Methoxybutane-1,3-dione

CAS No: 105-45-3
RTECS No: AK5775000
EC No: 607-137-00-0

C₅H₈O₃
Molecular mass: 116.1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Alcohol-resistant foam, powder, carbon dioxide.
EXPLOSION	Above 77°C explosive vapour/air mixtures may be formed.	Above 77°C use a closed system, ventilation.

EXPOSURE
Inhalation	Cough. Dizziness. Drowsiness. Headache. Sore throat.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin		Protective gloves.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes	Redness. Pain.	Safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion		Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water. (Extra personal protection: filter respirator for organic gases and vapours.)	Xi Symbol R: 36 S: (2-)26

EMERGENCY RESPONSE	STORAGE
NFPA Code: H2; F2; R0	Separated from oxidants.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

Chemical dangers
The substance decomposes on burning producing irritating fumes. Reacts with oxidants.

Occupational exposure limits
TLV not established.
MAK not established.

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour.

Inhalation risk
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.

Effects of short-term exposure
The substance is irritating to the eyes and the respiratory tract. Exposure may result in lowering of consciousness.

PHYSICAL PROPERTIES

ENVIRONMENTAL DATA

Boiling point: 171.7°C
Melting point: -27°C
Relative density (water = 1): 1.08
Solubility in water, g/100 ml: 50
Vapour pressure, kPa at 20°C: 0.17
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 77°C c.c.
Auto-ignition temperature: 280°C
Explosive limits, vol% in air: 1.4-14.5
Octanol/water partition coefficient as log Pow: -0.26

NOTES

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2003

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Updated by AS. Approved by EC. Last update: 23.01.2004