ICSC 0944 - ROTENONE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

ROTENONE

ICSC: 0944
_{April 2000}

Tubotoxine
Derris powder

CAS No: 83-79-4
RTECS No: DJ2800000
UN No: 2588
EC No: 650-005-00-2

C₂₃H₂₂O₆
Molecular mass: 394.45

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION

EXPOSURE		PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Confusion. Cough. Headache. Tremor. Laboured breathing. Nausea. Sore throat. Unconsciousness.	Local exhaust or breathing protection.	Fresh air, rest. Artificial respiration if indicated.
Skin	Redness.	Protective gloves.	First rinse with plenty of water, then remove contaminated clothes and rinse again. Rinse and then wash skin with water and soap.
Eyes	Redness.	Safety goggles, or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Abdominal cramps. Convulsions. Diarrhoea. Vomiting. (Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Sweep spilled substance into air tight containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P3 filter respirator for toxic particles). Do NOT let this chemical enter the environment.	T Symbol N Symbol R: 25-36/37/38-50/53 S: (1/2-)22-24/25-36-45-60-61 UN Hazard Class: 6.1 UN Pack Group: III	Do not transport with food and feedstuffs. Marine pollutant.

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III	Separated from food and feedstuffs. Well closed.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS CRYSTALS

Chemical dangers
The substance decomposes on burning producing irritating fumes.

Occupational exposure limits
TLV: 5 mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: IIb (not established but data is available); skin absorption (H); (DFG 2004).

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

Effects of short-term exposure
The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system, resulting in convulsions and respiratory depression.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the kidneys and liver.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Decomposes below boiling point Melting point: 165-166°C Density: 1.27 g/cm³ Solubility in water: none Octanol/water partition coefficient as log Pow: 4.10	The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. The substance may cause long-term effects in the aquatic environment.

NOTES

The substance is combustible but no flash point is available in literature.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Depending on the degree of exposure, periodic medical examination is suggested.
Card has been partly updated in April 2005. See sections Emergency response, Occupational Exposure Limits.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004

LEGAL NOTICE

Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

Updated by {ModOper}. Approved by {ModAppr}. Last update: {ModDate}