ICSC 0758 - VAMIDOTHION

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

VAMIDOTHION

ICSC: 0758
_{October 2001}

O,O-Dimethyl S-(2-(1-methylcarbamoylethylthio)ethyl) phosphorothioate
O,O-Dimethyl S-2-(1-N-methylcarbamoylethylmercapto)ethyl thiophosphate
N-Methyl O,O-dimethylthiolophosphoryl-5-thia-3-methyl-2-valeramide

CAS No: 2275-23-2
RTECS No: TF7900000
UN No: 2783
EC No: 015-059-00-8

C₈H₁₈NO₄PS₂
Molecular mass: 287.36

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, water spray, foam, carbon dioxide.
EXPLOSION

EXPOSURE		PREVENT DISPERSION OF DUST!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Laboured breathing. Convulsions. Unconsciousness.	Ventilation (not if powder), local exhaust, or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin	MAY BE ABSORBED! (See Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes		Face shield, or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Abdominal cramps. Vomiting. Diarrhoea. (Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT wash away into sewer. (Extra personal protection: P3 filter respirator for toxic particles.)	T Symbol N Symbol R: 21-25-50 S: (1/2-)36/37-45-61 UN Hazard Class: 6.1 UN Pack Group: III	Do not transport with food and feedstuffs.

EMERGENCY RESPONSE	STORAGE
Transport Emergency Card: TEC (R)-61GT7-III	Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS CRYSTALS

Chemical dangers
The substance decomposes on burning producing toxic fumes including nitrogen oxides, phosphorous oxides and sulfur oxides.

Occupational exposure limits
TLV not established.

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

Effects of short-term exposure
The substance may cause effects on the nervous system, resulting in convulsions and respiratory failure. Exposure at high levels may result in death. Cholinesterase inhibitor. The effects may be delayed. Medical observation is indicated.

Effects of long-term or repeated exposure
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Melting point: 46-48°C Solubility in water: very good Vapour pressure, at room temperature: negligible	The substance is harmful to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds and honey bees. Avoid release to the environment in circumstances different to normal use.

NOTES

Depending on the degree of exposure, periodic medical examination is indicated.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2002

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Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

Updated by AS. Approved by EC. Last update: 22.03.2002