ICSC 0600 - XYLIDINE (MIXED ISOMERS)

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

XYLIDINE (MIXED ISOMERS)

ICSC: 0600
_{April 2007}

Dimethylaniline
Aminodimethylbenzene
Dimethylphenylamine

CAS No: 1300-73-8
RTECS No: ZE8575000
UN No: 1711
EC No: 612-027-00-0

C₈H₁₁N / (CH₃)₂C₆H₃NH₂
Molecular mass: 121.2

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Water spray, carbon dioxide, foam, powder.
EXPLOSION	Above 90-98°C explosive vapour/air mixtures may be formed.	Above 90-98°C use a closed system, ventilation.

EXPOSURE		AVOID ALL CONTACT!
Inhalation	Dizziness. Drowsiness. Headache. Nausea.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! (See Ingestion)	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes		Safety spectacles or eye protection in combination with breathing protection.	Rinse with plenty of water (remove contact lenses if easily possible).
Ingestion	Blue lips or fingernails. Blue skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Chemical protection suit. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place.	EU classification T Symbol N Symbol R: 23/24/25-33-51/53 S: (1/2-)28-36/37-45-61 Note: C UN classification UN Hazard Class: 6.1 UN Pack Group: II GHS classification Signal: Warning Excl mark-Health haz Combustible liquid Harmful if swallowed Harmful in contact with skin Suspected of causing cancer May cause drowsiness or dizziness May cause damage to blood May cause damage to blood, liver and kidneys through prolonged or repeated exposure	Do not transport with food and feedstuffs.

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1711-L NFPA Code: H3; F1; R0	Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens, food and feedstuffs. Well closed. Store in an area without drain or sewer access.

IMPORTANT DATA

Physical State; Appearance
PALE YELLOWTO BROWN LIQUID, WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR.

Chemical dangers
The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants. Reacts with hypochlorites forming explosive chloroamines. Reacts with acids, acid anhydrides, acid chlorides and halogens. Attacks plastic and rubber.

Occupational exposure limits
TLV: (Inhalable fraction) and (vapour) 0.5 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2006).
MAK: skin absorption (H); Carcinogen category: 3A; (DFG 2006).

Routes of exposure
The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion.

Inhalation risk
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Effects of short-term exposure
Exposure at high levels could cause lowering of consciousness. Exposure at high levels may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

Effects of long-term or repeated exposure
The substance may have effects on the blood, resulting in anaemia. The substance may have effects on the kidneys and liver. This substance is possibly carcinogenic to humans.

PHYSICAL PROPERTIES

ENVIRONMENTAL DATA

Boiling point: 216-228°C
Relative density (water = 1): 0.97-1.07
Solubility in water, g/100 ml at 20°C: 0.4 - 15
Vapour pressure, Pa at 20°C: 4-130
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 90-98°C c.c.
Auto-ignition temperature: 520-590°C
Explosive limits, vol% in air: 1-7
Octanol/water partition coefficient as log Pow: 1.8- 2.2 (estimated)

This substance may be hazardous in the environment; special attention should be given to aquatic organisms.

NOTES

Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Commercial xylidine is a mixture of isomers where the 2,4-, 2,5- and 2,6-isomers dominate. See also ICSC 1519 (2,6-Xylidine), 1562 (2,4-Xylidine), 0453 (3,4-Xylidine), 1686 (2,5-Xylidine), 1687 (3,5-Xylidine).

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2006

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Updated by AS. Approved by GS. Last update: 29.01.2008