ICSC 0323 - PYRIDINE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

PYRIDINE

ICSC: 0323
_{December 2000}

Azine
Azabenzene

CAS No: 110-86-1
RTECS No: UR8400000
UN No: 1282
EC No: 613-002-00-7

C₅H₅N
Molecular mass: 79.1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames, NO sparks, and NO smoking.	Powder, alcohol-resistant foam, water in large amounts, carbon dioxide.
EXPLOSION	Vapour/air mixtures are explosive.	Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE
Inhalation	Cough. Dizziness. Headache. Nausea. Shortness of breath. Unconsciousness.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Burning sensation (further see Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes	Redness. Pain.	Safety spectacles. or face shield.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Abdominal pain. Diarrhoea. Vomiting. Weakness (further see Inhalation).	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. (Extra personal protection: self-contained breathing apparatus).	EU classification F Symbol Xn Symbol R: 11-20/21/22 S: (2-)26-28 UN classification UN Hazard Class: 3 UN Pack Group: II

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-98 NFPA Code: H 2; F 3; R 0	Fireproof. Separated from strong oxidants, strong acids. Cool. Dry. Well closed.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
The substance decomposes on burning producing toxic fumes (nitrogen oxides and hydrogen cyanide - see ICSC # 0492). The substance is a weak base. Reacts violently with strong oxidants and strong acids.

Occupational exposure limits
TLV: 1 ppm (as TWA) A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: 5 ppm, 16 mg/m³ Peak limitation category: II(2) (DFG 2005).

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

Effects of short-term exposure
The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system and gastrointestinal tract. Exposure far above the OEL could cause lowering of consciousness.

Effects of long-term or repeated exposure
The substance may have effects on the central nervous system, liver, kidneys.

PHYSICAL PROPERTIES

ENVIRONMENTAL DATA

Boiling point: 115°C
Melting point: -42°C
Relative density (water = 1): 0.98
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 2.0
Relative vapour density (air = 1): 2.73
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point: 20°C c.c.
Auto-ignition temperature: 482°C
Explosive limits, vol% in air: 1.8-12.4
Octanol/water partition coefficient as log Pow: 0.65

The substance is harmful to aquatic organisms.

NOTES

Pyridine can normally be detected by odour at levels well below the TLV. However, perception of the odour may decline quickly.
Depending on the degree of exposure, periodic medical examination is indicated.
Card has been partially updated in January 2008: see Ingestion First Aid.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2006

LEGAL NOTICE

Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

Updated by AS. Approved by GS. Last update: 29.01.2008