ICSC 0277 - HALOTHANE

[List of Chemicals] [Risk Notes] [Risk Phrases] [Safety Phrases] [Danger Symbols]

HALOTHANE

ICSC: 0277
_{November 2003}

2-Bromo-2-chloro-1,1,1-trifluoroethane
1-Bromo-1-chloro-2,2,2-trifluoroethane

CAS No: 151-67-7
RTECS No: KH6550000

BrClHC₂F₃
Molecular mass: 197.4

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRE FIGHTING
FIRE	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.		In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION			In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE		STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!
Inhalation	Confusion. Dizziness. Drowsiness. Nausea. Unconsciousness.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	Dry skin. Roughness.	Protective gloves.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes	Redness. Pain.	Safety goggles, or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	(See Inhalation).	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Refer for medical attention.

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: self-contained breathing apparatus).

EMERGENCY RESPONSE	STORAGE
	Keep in the dark. Ventilation along the floor.

IMPORTANT DATA

Physical State; Appearance
HIGHLY VOLATILE COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air.

Chemical dangers
The substance decomposes on heating producing toxic and corrosive fumes including hydrogen bromide, hydrogen chloride, hydrogen fluoride. The substance decomposes under the influence of light.

Occupational exposure limits
TLV: 50 ppm; A4; (ACGIH 2003).
MAK: 5 ppm, 41 mg/m³; Peak limitation category: II(8); Pregnancy risk group: B; (DFG 2002).

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of short-term exposure
The substance is irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels may result in unconsciousness.

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the liver, resulting in liver impairment. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Boiling point: 50°C Melting point: -118°C Relative density (water = 1): 1.87 Solubility in water, g/100 ml: 0.45 Vapour pressure, kPa at 20°C: 32.4 Relative vapour density (air = 1): 2.87 Relative density of the vapour/air-mixture at 20°C (air = 1): 2.9 Octanol/water partition coefficient as log Pow: 2.30

NOTES

0.01% Thymol is used as a stabilizer.
Fluothane is a trade name.
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.
Check oxygen content before entering area.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2003

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Updated by AS. Approved by EC. Last update: 23.01.2004