ICSC 0630 - 2-AMINO-5-CHLOROTOLUENE

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2-AMINO-5-CHLOROTOLUENE	ICSC: 0630 (April 2007)
4-Chloro-o-toluidine 4-Chloro-2-methylaniline

CAS #: 95-69-2

UN #: 2239

EC Number: 202-441-6

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, dry powder, carbon dioxide.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Red urine. Frequent, sudden and painful urination. Abdominal pain. Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Drowsiness.	Use breathing protection.	Fresh air, rest. Refer immediately for medical attention.
Skin	Redness. MAY BE ABSORBED! See Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention.
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Sweep spilled substance into covered containers. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.	According to UN GHS Criteria DANGER Harmful if swallowed or in contact with skin May cause genetic defects May cause cancer Causes damage to bladder and red blood cells Harmful to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Cool. Separated from food and feedstuffs. See Chemical Dangers. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
PACKAGING
Note: E

2-AMINO-5-CHLOROTOLUENE

ICSC: 0630

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS TO BROWN SOLID IN VARIOUS FORMS OR LIQUID Physical dangers Chemical dangers Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. Reacts violently with chloroformic acid esters, strong oxidants, acid anhydrides, acids and acid chlorides.	Formula: C₇H₈ClN/ ClC₆H₃(CH₃)NH₂ Molecular mass: 141.6 Boiling point: 241°C Melting point: 29-30°C Density: 1.19 g/cm³ Solubility in water, g/100ml at 25°C: 0.095 (very poor) Vapour pressure, Pa at 25°C: 5.5 Relative vapour density (air = 1): 4.9 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 99°C c.c. Auto-ignition temperature: 560°C Octanol/water partition coefficient as log Pow: 2.27

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS TO BROWN SOLID IN VARIOUS FORMS OR LIQUID

Physical dangers

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. Reacts violently with chloroformic acid esters, strong oxidants, acid anhydrides, acids and acid chlorides.

Formula: C₇H₈ClN/ ClC₆H₃(CH₃)NH₂
Molecular mass: 141.6
Boiling point: 241°C
Melting point: 29-30°C
Density: 1.19 g/cm³
Solubility in water, g/100ml at 25°C: 0.095 (very poor)
Vapour pressure, Pa at 25°C: 5.5
Relative vapour density (air = 1): 4.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 99°C c.c.
Auto-ignition temperature: 560°C
Octanol/water partition coefficient as log Pow: 2.27

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body through the skin, by inhalation and by ingestion. Effects of short-term exposure May cause mechanical irritation to the skin, respiratory tract and eyes (as a solid). The substance may cause effects on the bladder. This may result in haemorrhagic inflammation. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.	Inhalation risk A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Effects of long-term or repeated exposure May cause heritable genetic damage to human germ cells.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body through the skin, by inhalation and by ingestion.

Effects of short-term exposure
May cause mechanical irritation to the skin, respiratory tract and eyes (as a solid). The substance may cause effects on the bladder. This may result in haemorrhagic inflammation. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Effects of long-term or repeated exposure
May cause heritable genetic damage to human germ cells.

OCCUPATIONAL EXPOSURE LIMITS
MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A

ENVIRONMENT
The substance is harmful to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 45-23/24/25-68-50/53; S: 53-45-61-60

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