ICSC 0458 - 2,4-XYLENOL

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2,4-XYLENOL	ICSC: 0458 (July 2003)
2,4-Dimethylphenol m-Xylenol 1-Hydroxy-2.4-dimethylbenzene

CAS #: 105-67-9

UN #: 2261

EC Number: 203-321-6

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, alcohol-resistant foam, carbon dioxide.

PREVENT DISPERSION OF DUST! PREVENT GENERATION OF MISTS! STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Burning sensation. Cough. Sore throat. Shortness of breath. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin	Redness. Pain. Skin burns.	Protective clothing. Protective gloves.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness. Pain. Severe burns.	Wear safety goggles, face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Burning sensation. Abdominal pain. Nausea. Vomiting. Shock or collapse.	Do not eat, drink, or smoke during work.	Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. If liquid: collect leaking liquid in covered plastic containers.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Separated from food and feedstuffs, acid anhydrides, acid chlorides, bases and oxidants.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

2,4-XYLENOL

ICSC: 0458

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance YELLOW-TO-BROWN LIQUID OR COLOURLESS CRYSTALS. Physical dangers Chemical dangers Decomposes on burning. This produces toxic gases and irritating fumes. Reacts with acid anhydrides, acid chlorides, bases and oxidants.	Formula: C₈H₁₀O / (CH₃)₂C₆H₃OH Molecular mass: 122.17 Boiling point: 211.5°C Melting point: 25.4-26°C Density: 0.97 g/cm³ Solubility in water, g/100ml at 25°C: 0.79 Vapour pressure, Pa at 20°C: 8 Flash point: >112°C c.c. Auto-ignition temperature: 599°C Explosive limits, vol% in air: 1.1-6.4 Octanol/water partition coefficient as log Pow: 2.3

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
YELLOW-TO-BROWN LIQUID OR COLOURLESS CRYSTALS.

Physical dangers

Chemical dangers
Decomposes on burning. This produces toxic gases and irritating fumes. Reacts with acid anhydrides, acid chlorides, bases and oxidants.

Formula: C₈H₁₀O / (CH₃)₂C₆H₃OH
Molecular mass: 122.17
Boiling point: 211.5°C
Melting point: 25.4-26°C
Density: 0.97 g/cm³
Solubility in water, g/100ml at 25°C: 0.79
Vapour pressure, Pa at 20°C: 8
Flash point: >112°C c.c.
Auto-ignition temperature: 599°C
Explosive limits, vol% in air: 1.1-6.4
Octanol/water partition coefficient as log Pow: 2.3

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, by ingestion and through the skin. Effects of short-term exposure The substance is corrosive to the skin, respiratory tract and eyes. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes.	Inhalation risk No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact may cause skin sensitization.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin.

Effects of short-term exposure
The substance is corrosive to the skin, respiratory tract and eyes. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes.

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization.

OCCUPATIONAL EXPOSURE LIMITS
TLV: (inhalable fraction and vapour): 1 ppm as TWA; (DSEN); A3 (confirmed animal carcinogen with unknown relevance to humans)

ENVIRONMENT
The substance is toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish.

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 24/25-34-51/53; S: (1/2)-26-36/37/39-45-61; Note: C

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