|ARSENIC TRIOXIDE||ICSC: 0378 (November 2008)|
Arsenous oxide anhydride
Arsenous acid anhydride
| CAS #: 1327-53-3
| UN #: 1561
|EC Number: 215-481-4
|ACUTE HAZARDS||PREVENTION||FIRE FIGHTING|
|FIRE & EXPLOSION||Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.||In case of fire in the surroundings, use appropriate extinguishing media.|
|PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!|
|Inhalation||Burning sensation behind the breastbone. Cough. Dizziness. Headache. Shortness of breath. Sore throat. Weakness. See Ingestion. Symptoms may be delayed. See Notes.||Use closed system and ventilation.||Fresh air, rest. Half-upright position. Refer for medical attention.|
|Skin||Redness. Pain. Blisters. Skin burns.||Protective gloves. Protective clothing.||Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .|
|Eyes||Redness. Pain. Burns.||Wear face shield or eye protection in combination with breathing protection if powder.||Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.|
|Ingestion||Burns in mouth and throat. Abdominal cramps. Diarrhoea. Nausea. Vomiting. Shock or collapse.||Do not eat, drink, or smoke during work. Wash hands before eating.||Rinse mouth. Do NOT induce vomiting. Refer for medical attention . See Notes.|
|SPILLAGE DISPOSAL||CLASSIFICATION & LABELLING|
|Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable, plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.||
According to UN GHS Criteria
DANGERToxic if swallowed
Causes severe skin burns and eye damage
Suspected of causing genetic defects
May cause cancer
May damage fertility or the unborn child
Causes damage to blood, central nervous and cardiovascular system and liver
May cause respiratory irritation
Causes damage to the bone marrow, the central nervous system, the kidneys and the liver through prolonged or repeated exposure
Very toxic to aquatic life
|Provision to contain effluent from fire extinguishing. Separated from combustible substances, reducing agents and food and feedstuffs. Well closed. Store only in original container. Store in an area without drain or sewer access.|
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
|ARSENIC TRIOXIDE||ICSC: 0378|
|PHYSICAL & CHEMICAL INFORMATION|
Physical State; Appearance
|EXPOSURE & HEALTH EFFECTS|
Routes of exposure
Effects of short-term exposure
Effects of long-term or repeated exposure
|OCCUPATIONAL EXPOSURE LIMITS|
TLV: 0.01 mg/m3, as TWA; A1 (confirmed human carcinogen); BEI issued.
MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A.
EU-OEL: (inhalable fraction): 0.01 mg/m3 as TWA; (see Notes)
|The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds, fish and mammals. It is strongly advised not to let the chemical enter into the environment.|
|Do NOT take working clothes home.
Physical properties depend on crystalline form of the substance.
The symptoms of acute poisoning appear ½ to 1 hour after the exposure but may be delayed many hours.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Refer for medical attention if breathing difficulties and/or fever develop.
Depending on the degree of exposure, periodic medical examination is suggested.
The recommendations on this Card also apply to inorganic trivalent arsenic compounds (arsenites).
For the copper smelting sector, the EU OEL value shall apply from 11 July 2023.
Symbol: T+, N; R: 45-28-34-50/53; S: 53-45-60-61; Note: E
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