ICSC 0521 - NICOTINE TARTRATE

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NICOTINE TARTRATE	ICSC: 0521 (November 2023)
Nicotine acid tartrate Nicotine bitartrate (2R,3R)-2,3-dihydroxybutanedioic acid;3-(1-methylpyrrolidin-2-yl)pyridine

CAS #: 65-31-6

UN #: 1659

EC Number: 200-607-2

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, alcohol-resistant foam, carbon dioxide.

PREVENT DISPERSION OF DUST! STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough.	Use local exhaust, ventilation or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin		Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Burning sensation. Confusion. Nausea. Vomiting. Excessive salivation. Diarrhoea. Sweating. Dizziness. Convulsions. Drowsiness. Respiratory arrest.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: complete protective clothing and particulate filter respirator adapted to the airborne concentration of the substance. If appropriate, moisten first to prevent dusting. Sweep spilled substance into covered containers. Do NOT wash away into sewer. Then store and dispose of according to local regulations.	According to UN GHS Criteria Toxic if swallowed Harmful if inhaled Causes serious eye irritation May cause damage to cardiovascular system and central nervous system Toxic to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Separated from strong oxidants and food and feedstuffs. Provision to contain effluent from fire extinguishing.
PACKAGING
Do not transport with food and feedstuffs. Put breakable packaging into closed unbreakable container.

NICOTINE TARTRATE

ICSC: 0521

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE FLAKES. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes of nitrogen oxides and carbon monoxide. Reacts violently with strong oxidants. This generates explosion hazard.	Formula: C₁₀H₁₄N₂ . 2C₄H₆O₆ Molecular mass: 462.5 Melting point: 89 - 101°C Solubility in water: very soluble Auto-ignition temperature: 244°C Boiling point: 141.3 - 302°C (estimated) Flash point: 143°C Relative density (water = 1): 1.495 (20°C) Octanol/water partition coefficient as log Pow: -7.25

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE FLAKES.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes of nitrogen oxides and carbon monoxide. Reacts violently with strong oxidants. This generates explosion hazard.

Formula: C₁₀H₁₄N₂ . 2C₄H₆O₆
Molecular mass: 462.5
Melting point: 89 - 101°C
Solubility in water: very soluble
Auto-ignition temperature: 244°C
Boiling point: 141.3 - 302°C (estimated)
Flash point: 143°C
Relative density (water = 1): 1.495 (20°C)
Octanol/water partition coefficient as log Pow: -7.25

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. Effects of short-term exposure The substance is severely irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. This may result in central nervous system depression and respiratory depression. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure Animal tests show that this substance possibly causes toxic effects upon human reproduction.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. This may result in central nervous system depression and respiratory depression. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes toxic effects upon human reproduction.

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is toxic to aquatic organisms.

NOTES
Other CAS number: 6019-06-3 .

ADDITIONAL INFORMATION

EC Classification

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