Azides - 7 entries found
Your search criteria are
Smith R.P., Wilcox D.E.
Toxicology of selected nitric oxide-donating xenobiotics, with particular reference to azide
Although nitric oxide (NO) is responsible for a variety of normal physiological functions, it has also been implicated in several pathophysiological processes. Recently, a variety of xenobiotics have been shown to owe their biological activity in vivo to their biotransformation to NO. As reviewed here, NO does not appear to contribute importantly to the toxicity of NO donors nitrite, hydroxylamine or nitroprusside. However, it is not clear if NO generated in vivo from sodium azide contributes in a major way to its toxicity. Some evidence suggests a tendency for azide to produce low-grade cumulative toxicity. Azide is widely used as a preservative in aqueous laboratory reagents and as a propellant in automobile air bags and aircraft escape chutes. To protect workers who handle these devices and others who may come into contact with the sodium azide propellant in these systems, the rudimentary knowledge of azide toxicity needs to be expanded.
Critical Reviews in Toxicology, Oct. 1994, Vol.24, No.4, p.355-377. 129 ref.
Potential industrial carcinogens and mutagens
176 industrial organic chemicals are examined and collated in terms of 21 major groupings and 38 structural subgroupings. Information is given on: synthesis, trace impurities, production volumes, use, occurrence, chemical and biological reactivity, estimated populations at risk, exposure limits in various countries, carcinogenicity and mutagenicity test systems. Combination effects in chemical carcinogenesis, epidemiology, and risk assessment are discussed.
Studies in Environmental Science 4, Elsevier Scientific Publishing Company, P.O. Box 211, 1000 AE Amsterdam, Netherlands, 1979. 534p. Illus. 2750 ref. Price: US$66.75; Glds.150.00.
Santodonato J., Hoecker J.E., Orzel D., Meylan W.
Information profiles on potential occupational hazards - Classes of chemicals.
Chemical notations, production and use information, biological effects of exposure and bibliographies are provided for potentially hazardous substances in the classes: aldehydes; aliphatic imines; alkenes; aluminium and compounds; copper and compounds; cyclic alkenes; glycol ethers; glycols; indium and compounds; inorganic azides; inorganic chlorine compounds; inorganic sulfur compounds; lithium and compounds; lubricant, oil and grease additives; mercaptobenzothiazoles; nitronaphthalenes; nitroparaffins; organic acids; organophosphate compounds; palladium and compounds; phthalates; platinum and compounds; silver and compounds; tellurium and compounds; thioureas; titanium and compounds; trimethylbenzenes; uranium and compounds; xylenols.
Contract No.210-77-0003. National Institute for Occupational Safety and Health, 5600 Fishers Lane, Rockville, Maryland 20852, USA, avr. 1978. 341p. Illus. 502 ref.
Hazardous chemical reactions - Triazoles and tetrazoles
Réactions chimiques dangereuses - Tri- et tétrazoles. [in French]
Enumeration and description of the possible reactions (explosion, detonation, deflagration), which may be spontaneous or due to heat or friction, of 32 triazoles, tetrazoles or derivatives of these compounds. The references used are listed for each reaction.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 3rd quarter 1978, No.92, Note No.1134-92-78, p.445-449.
Dangerous chemical reactions - 52. Azido compounds
Réactions chimiques dangereuses - 52. Composés azido. [in French]
Listing and description of possible reactions (combustion or explosive decomposition) of 44 organic and inorganic azides, in contact with inorganic substances, due to heat or shock, etc. References are given for each reaction.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 2nd quarter 1978, No.91, Note No.1121-91-78, p.319-324.
NIOSH current intelligence bulletin reprints - Bulletins 1 thru 18.
These reprints include the initial notification of the hazards presented, the background (studies, toxicity in animals and humans, workers and industries subject to exposure, supplier and users of the substances) and bibliographies. Studies in progress are mentioned and recommendations are given for chloroprene, trichloroethylene, ethylene dibromide, chrome pigments, asbestos, hexamethylphosphoric triamide, polychlorinated biphenyls, 4,4-diaminodiphenylmethane, chloroform, radon daughters, dimethylcarbamoyl chloride, diethylcarbamoyl chloride, explosive azides, inorganic arsenic, nitrosamines in cutting fluids, metabolic precursors of 2-naphthylamine, 2-nitropropane, acrylonitrile.
DHEW (NIOSH) Publication No.78-127, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, 1 Mar. 1978. 125p. 104 ref.
Hazardous chemical reactions - 49. Hydrazoic acid and azides
Réactions chimiques dangereuses - 49. Acide azothydrique et azotures. [in French]
Enumeration and description of the possible reactions (ignition or explosive decomposition) of hydrazoic acid and 55 azides as a result of heat, light or impact, or contact with various organic or mineral substances. The references used are listed for each reaction.
Cahiers de notes documentaires - Sécurité et hygiène du travail, 1st quarter 1978, No.90, Note No.1103-90-78, p.137-148.