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Base de datos CISDOC

ID (ISN) del documento62814
Número CIS 94-1225
ISSN - Título de la serie 0025-7818 - Medicina del lavoro
Año 1993
Número de serie
Autor(es) Franco G., Fonte R., Ghittori S.
Título Drinking habits and occupational exposure to inhalation anesthetics at low doses
Información bibliográfica Nov.-Dec. 1993, Vol.84, No.6, p.463-472. Illus. 54 ref.
Resumen The aim of this study was to evaluate certain indicators of hepatic (serum aminotransferase activities) and haematological (erythrocyte mean corpuscular volume) changes among health care personnel exposed to inhalation anaesthetics (nitrous oxide and isoflurane). Workers (172) in a hospital were divided into four groups according to exposure and drinking habits: (1) non-drinkers and unexposed subjects; (2) drinkers and unexposed subjects; (3) non-drinkers and exposed subjects; (4) drinkers and exposed subjects. Aminotransferase activity or mean erythrocyte size were not affected by anaesthetics exposure. Increased aspartateaminotransferase (AST) values among unexposed drinkers were related to alcohol intake. This observation was confirmed by the relationship between AST behaviour and quantitative alcohol intake. Thus, when studying any effect involving functions related to the biotransformation of xenobiotics, in which the liver plays a primary role, the importance of establishing the exact daily amount of ethanol intake is stressed.
Descriptores (primarios) metabolización; etanol; anestésicos por inhalación; sinergismo; isoflurano; alteraciones de la sangre; personal de los servicios de salud; óxido nitroso
Descriptores (secundarios) actividad enzimática; recuento de glóbulos y plaquetas
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaItalia
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Inorganic substances
Health care services
Blood diseases
Ethers
Alcohols