ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento61883
Número CIS 94-641
ISBN(s) 90-399-0518-5
Año 1993
Número de serie Arbeidsinspectie RA 3/93
Department of Social Affairs and Employment, Directorate-General of Labour (Ministerie van Sociale Zaken en Werkgelegenheid, Directoraat-Generaal van de Arbeid)
Título Health-based recommended occupational exposure limit for pyridine
Información bibliográfica SDU Uitgeverij Plantijnstraat, Afdeling Verkoop Publikaties Arbeidsinspectie, Postbus 20014, 2500 EA Den Haag, Netherlands, 1993. 8+20p. Illus. Bibl.ref.
Resumen This publication (prepared in cooperation between the Dutch Expert Committee for Occupational Standards (DEC) and the Swedish Criteria Group (SCG), whose criteria document on pyridine in the series Arbete och hälsa 1991:49 by M. Warholm has already been abstracted as CIS 93-610) presents an evaluation of the health hazards of exposure to pyridine. This substance is mainly used as a solvent and is also an intermediate in the production of e.g. pharmaceutical and agricultural chemicals. Attention is given to: identity, physical and chemical properties, analytical methods; toxicokinetic data; general toxicological effects in animal and humans (short-term exposure and long-term exposure); effects on organs; biochemical effects; reproductive effects and effects on pregnancy; mutagenicity; carcinogenicity; evaluation of human health risks. The critical health effect of pyridine seems to be its effect on the central nervous system and the liver. Based on the data available, the Dutch Expert Committee recommends a health-based occupational exposure limit for pyridine of 1mg/m3 (0.3ppm), 8h-TWA, with a skin notation. Detailed summary in Dutch.
Descriptores (primarios) valores umbrales; Suecia; Países Bajos; efectos biológicos; determinación de los límites de la exposición; riesgos para la salud; piridina
Descriptores (secundarios) efectos tóxicos; efectos neurotóxicos; revisión bibliográfica; substancias irritantes; documentación de base; lesiones hepáticas; lesiones renales; valoración de la toxicidad; informe
Tipo de documento E - Libros, informes, actas
País / Estado o ProvinciaPaíses Bajos; Suecia
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Occupational exposure limits
Heterocyclic compounds