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Base de datos CISDOC

ID (ISN) del documento61645
Número CIS 94-209
ISSN - Título de la serie 0271-3586 - American Journal of Industrial Medicine
Año 1993
Número de serie
Autor(es) Cheng W.N., Coenraads P.J., Hao Z.H., Lui G.F.
Título A health survey of workers in the pentachlorophenol section of a chemical manufacturing plant
Información bibliográfica July 1993, Vol.24, No.1, p.81-92. Illus. 52 ref.
Resumen During 1968 to 1985, 109 workers who had been engaged in the production of pentachlorophenol, using non-gamma isomers of hexachlorocyclohexane (BHC) as the raw material, were surveyed. Endemic chloracne among them had been noted since 1974. The prevalence of chloracne was 73.4% (80/109) in total and 95.2% (20/21) in a trichlorobenzene (TCB) tank area where dioxin (PCDD) and dibenzofuran (PCDF) levels were thousands of ppm. It seems that PCDDs and PCDFs have not previously been reported from thermal decomposition of BHC. Urinary porphyrins were significantly higher among exposed workers than among the controls but there was no significant difference between the workers with chloracne and those without. The conduction velocities of the median motor nerves were much slower among the workers in the TCB tank area where the highest PCDD contamination appeared. The mortality study cohort was relatively young. Based on the three deaths observed during the follow-up, no association could be drawn.
Descriptores (primarios) industria química; triclorobenceno; pentaclorofenol; dibenzofuranos; exposición; acné clórico; efectos dermatológicos; dosificación en la orina; dioxinas
Descriptores (secundarios) China; dermatosis; paises en desarrollo; exámenes dermatológicos; tests de exposición; estudio de cohorte
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaChina; Países Bajos
Tema(s) Patología profesional
Broad subject area(s) Medicina del trabajo, epidemiología
Navegación por categoria(s) Chemical industry
Skin diseases
Halogenated hydrocarbons
Phenols and phenolic compounds
Heterocyclic compounds