| ID (ISN) del documento | 61166 |
| Número CIS |
93-1874 |
| ISSN - Título de la serie |
0096-1736 - Journal of Occupational Medicine |
| Año |
1993 |
| Número de serie |
|
| Autor(es) |
Bi W.F., Rao J.Y., Hemstreet G.P., Fang P., Asal N.R., Zang M., Min K.W., Ma Z., Lee E., Li G., Hurst R.E., Bonner R.B., Wang Y., Fradet Y., Yin S. |
| Título |
Field molecular epidemiology - Feasibility of monitoring for the malignant bladder cell phenotype in a benzidine-exposed occupational cohort |
| Información bibliográfica |
Jan. 1993, Vol.35, No.1, p.20-27. Illus. 25 ref. |
| Resumen |
The primary objective of this study was to demonstrate the feasibility of using cellular and molecular methods in combination with medical and epidemiological methods in field studies to identify cancer cases, risk factors, and markers. A previously identified cohort of Chinese workers exposed to benzidine was studied by medical and exposure history questionnaires and interviews, physical examinations and sample collection for laboratory analysis. Three groups were included in this study: 23 bladder cancer cases who had been exposed to benzidine, 20 subjects with previous exposure history but not previously diagnosed with bladder cancer and a group of non-exposure and non-bladder cancer controls. Very sophisticated molecular techniques for measurement of DNA ploidy, tumour antigens, and oncogene proteins was successfully applied. |
| Descriptores (primarios) |
tumor de vejiga; encuesta epidemiológica; tumores; pruebas biológicas y médicas; bencidina; factores de riesgo |
| Descriptores (secundarios) |
China; encuesta por cuestionario; citología; citología urinaria; detección por fluorescencia; exámenes médicos |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Canadá; China; Estados Unidos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Diseases of the kidney and the urinary system
Aromatic amines
|
