| ID (ISN) del documento | 60091 |
| Número CIS |
93-829 |
| ISSN - Título de la serie |
0002-8894 - American Industrial Hygiene Association Journal |
| Año |
1992 |
| Número de serie |
|
| Autor(es) |
Owen C.V., Acquavella J.A., Lynch J., Bird M.G. |
| Título |
An industrial hygiene methodology developed in support of a retrospective morbidity case-control study |
| Información bibliográfica |
Sep. 1992, Vol.53, No.9, p.540-547. 29 ref. |
| Resumen |
This study investigated a potentially increased incidence of colorectal cancer among employees who manufactured polypropylene. The design of the case-control study provided an innovative industrial hygiene approach to circumvent the problems of estimating exposures, problems which are typical of retrospective epidemiological case-control studies. The industrial hygiene methodology included assessing historical exposures, developing an exposure estimating matrix, selecting candidate aetiological agents based on a joint toxicological and industrial hygiene review, administering a work activity questionnaire, calculating exposure scores, and conducting a statistical analysis. The study design also provided an additional exposure measurement independent of the toxicological and industrial hygiene review. This provided an opportunity to compare the likelihood of exposure misclassification and, as expected, showed that a more detailed exposure estimate resulted in less misclassification. |
| Descriptores (primarios) |
cáncer de recto; polipropileno; etiología; exposición de larga duración; valoración de la exposición; valoración de la higiene del trabajo; epidemiología |
| Descriptores (secundarios) |
polimerización; descripción del procedimiento; catalogo de substancias químicas |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Estados Unidos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Gastrointestinal diseases
Exposure evaluation
Epidemiology
|
