ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento59073
Número CIS 92-1986
ISSN - Título de la serie Journal of the National Cancer Institute
Año 1992
Número de serie
Autor(es) Smith A.H., Patterson D.G., Warner M.L., MacKenzie R., Needham L.L.
Título Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels of New Zealand pesticide applicators and their implication for cancer hypotheses
Información bibliográfica 15 Jan. 1992, Vol.84, No.2, p.104-108. Illus. 40 ref.
Resumen The phenoxyherbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) is a widely used pesticide. Little is known about the extent of exposure to the 2,4,5-T contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a potent animal carcinogen. The study determined whether the blood serum levels of TCDD in 2,4,5-T applicators were greater than those of a control group not involved in 2,4,5-T spraying. Nine of 548 New Zealand applicators were selected who had sprayed 2,4,5-T for a range of 83-372 months. Results showed that the average serum level of TCDD for applicators was almost 10 times that of the control subjects, while the average levels of all other congeners and isomers measured in the two groups did not differ substantially. Increased risks of cancer from brief exposure to phenoxy herbicides reported in other countries are probably not attributable to the TCDD that contaminates 2,4,5-T. It cannot be determined from these results, however, whether TCDD exposure from prolonged use of 2,4,5-T poses significant health risks.
Descriptores (primarios) herbicidas; ácido triclorofenoxiacético; dosificación en la sangre; pesticidas; exposición de larga duración; tetraclorodibenzodioxina
Descriptores (secundarios) Nueva Zelandia; tumores; alteraciones del suero
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaNueva Zelandia; Estados Unidos
Tema(s) Agricultura, pesca, cría de ganado
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Heterocyclic compounds
Agricultural chemicals