| ID (ISN) del documento | 57865 |
| Número CIS |
92-464 |
| ISSN - Título de la serie |
0021-5287 - Japanese Journal of Urology |
| Año |
1991 |
| Número de serie |
|
| Autor(es) |
Matsuoka K., Etoh K., Yoshitake N. |
| Título |
Clinical analysis of patients with occupational urothelial tumours |
| Título original |
Shokugyōsei nyōro jōhi shuyō no kaiseki [en japonés] |
| Información bibliográfica |
20 July, 1991, Vol.82, No.7, p.1118-1124. 28 ref. |
| Resumen |
The incidence of occupational urothelial carcinoma and the accompanying problems were studied in workers who had manufactured or handled dyestuffs at a chemical factory. 25 cases of urothelial carcinomas, mainly consisting of urinary bladder carcinoma, occurred among 398 men who were examined at regular intervals; the incidence rate was 6.3%. The mean age at onset, mean period of exposure to aromatic compounds and mean latent period were 61 years, 7.2 years and 30 years, respectively. The highest incidences were associated with prolonged exposure and smoking. As the age at entry in the workforce advanced, the latent period became shorter. The incidence was highest in workers exposed to 2 or 3 aromatics, followed by those exposure to benzidine and alpha-naphthylamine. No urothelial carcinoma occured in those who worked with beta-naphthylamine. 94% of the carcinomas were superficial and transurethral resections were performed for bladder carcinomas. The recurrence rate in the bladder cavity after surgery was 39%, which is almost the same as for non-occupational bladder carcinomas; however, the recurrence rate in the upper urinary tract was relatively high (26%). The 5, 10, 20 year survival rates were 92%, 72% and 47%, respectively. Three of the 8 patients dying of cancer died of double cancer. The incidence rate for non-urothelial cancer was 5.7%. |
| Descriptores (primarios) |
enfermedades del aparato genitourinario; aminas aromáticas; industria de los colorantes; cáncer renal; tumor de vejiga; tumores epiteliales |
| Descriptores (secundarios) |
naftil-1 amina; naftil-2 amina; bencidina; investigación de higiene del trabajo; enfermedades del uréter |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Japón |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Chemical industry
Diseases of the kidney and the urinary system
Aromatic amines
|
