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Base de datos CISDOC
| ID (ISN) del documento | 57404 |
| Número CIS |
92-224 |
| ISSN - Título de la serie |
0140-6736 - Lancet |
| Año |
1991 |
| Número de serie |
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| Autor(es) |
Saracci R., Kogevinas M., Bertazzi P., Bueno de Mesquita B.H., Coggon D., Green L.M., Kauppinen T., L'Abbé K.A., Littorin M., Lynge E., Mathews J.D., Neuberger M., Osman J., Pearce N., Winkelmann R. |
| Título |
Cancer mortality in workers exposed to chlorophenoxy herbicides and chlorophenols |
| Información bibliográfica |
26 Oct. 1991, Vol.338, No.8774, p.1027-1032. 35 ref. |
| Resumen |
This paper reports a historical cohort study of mortality in an international register of 18,910 chlorophenoxy herbicide production workers or sprayers from 10 countries. Exposure was reconstructed through questionnaires, factory or spraying records and job histories. A non-significant increase, based on 4 observed deaths, was noted for soft-tissue sarcoma. Increased risks were found for some uncommon neoplasms, but results are difficult to interpret because of the small numbers. The excess of soft-tissue sarcomas among sprayers is compatible with a causal role of chlorophenoxy herbicides but the excess does not seem to be specifically associated with those herbicides probably contaminated by the toxic dioxin TCDD. |
| Descriptores (primarios) |
herbicidas; tumores; riesgos para la salud; clorofenoles |
| Descriptores (secundarios) |
ácido cloro-4 metil-2 fenoxiacético; tricloro-2,4,6 fenol; silvex; ácido (dicloro-2,4 fenoxi)-4 butanoico; ácido fenoxibutírico; tetracloro-2,3,4,6 fenol; pentaclorofenol; ácido diclorofenoxiacético; ácido triclorofenoxiacético; tetraclorodibenzodioxina; sarcomas; encuesta epidemiológica; dicloro-2,4 fenol; triclorofenol; dicloropropiónico |
| Tipo de documento |
D - Artículos periódicos |
| País / Estado o Provincia | Australia; Austria; Canadá; Dinamarca; Finlandia; Francia; Reino Unido; Italia; Países Bajos; Nueva Zelandia; Suecia |
| Tema(s) |
Patología profesional
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| Broad subject area(s) |
Riesgos químicos
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| Navegación por categoria(s) |
Agricultural chemicals
Phenols and phenolic compounds
Alcohols
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