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Base de datos CISDOC

ID (ISN) del documento57267
Número CIS 92-182
ISSN - Título de la serie 0007-1072 - British Journal of Industrial Medicine
Año 1990
Número de serie
Autor(es) Hnizdo E.
Título Combined effect of silica dust and tobacco smoking on mortality from chronic obstructive lung disease in gold miners
Información bibliográfica Oct. 1990, Vol.47, No.10, p.656-664. Illus. 24 ref.
Resumen A sample of 2209 white South African gold miners aged 45-54 between 1968-71, who started to work in mines during 1936-43, was investigated from 1968-71 to Decembber 1986. The effect of silica dust and tobacco smoking on mortality from chronic obstructive lung disease (COLD) was assessed. The combined effect of dust exposure before 1950 and years of cigarette smoking on mortality from COLD was best estimated by the multiplicative model, indicating that the 2 exposures act synergistically. All those that died of the disease were smokers. According to the estimates of attributable risk about 5% of the deaths from COLD were from the effect of dust, 34% were from smoking, and 59% were from the combined effect of dust and smoking. In conclusion, the results indicate that workers exposed to silica dust who smoke are at higher risk of dying from COLD than smokers not exposed to silica dust, as the 2 exposures act synergistically in causing COLD.
Descriptores (primarios) síndrome obstructivo; sílice; fumadores; formas crónicas; minas de oro; neumopatías; polvos respirables; sinergismo; mortalidad
Descriptores (secundarios) Sudáfrica; síntomas; pruebas funcionales respiratorias; valoración del riesgo; trabajos subterráneos
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaSudáfrica
Tema(s) Polvos, aerosoles
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying
Tabaquismo