| ID (ISN) del documento | 54976 |
| Número CIS |
90-2005 |
| ISBN(s) |
91-7045-037-4 |
| Año |
1989 |
| Número de serie |
Arbete och hälsa 1989:25
|
| Autor(es) |
Garberg P., Högberg J., Lundberg I., Lundberg P. |
| Título |
NIOH and NIOSH basis for an occupational health standard: Di(2-ethylhexyl)phthalate (DEHP) |
| Información bibliográfica |
Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1989. Also available from: Superintendent of Documents, US Government Printing Office, Washington D.C. 20402, USA. 53p. 131 ref. |
| Resumen |
Literature survey on di(2-ethylhexyl)phthalate (DEHP), to be used as background information for discussions on occupational exposure limits in the USA and Sweden. Data on occupational exposure levels and effects on humans are limited. DEHP is hydrolysed to the monoethylhexyl product and further oxidised. No accumulation has been observed. DEHP has a low acute toxicity. Long-term exposure to rats causes testicular atrophy. DEHP is carcinogenic and teratogenic in rodents. Most genotoxicity tests have been negative. However, certain tests have indicated that DEHP may affect the genome in vitro. |
| Descriptores (primarios) |
ftalato de bis(etilhexilo); limitación de la exposición; toxicología |
| Descriptores (secundarios) |
revisión bibliográfica; Suecia; Estados Unidos; atrofia testicular; documentación de base; efectos genéticos; efectos teratogénicos; efectos cancerígenos; determinación de los límites de la exposición |
| Tipo de documento |
F - Notas informativas, directrices prácticas, normas |
| País / Estado o Provincia | Suecia; Estados Unidos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Esters and salts
Genetic factors in reaction to exposures
Phthalates
|
