ID (ISN) del documento | 54910 |
Número CIS |
90-1968 |
ISBN(s) |
92-825-8909-9 (Eng); 92-825-8910-2 (fr) |
Año |
1988 |
Número de serie |
EUR 11659
|
Título |
Indicators for assessing exposure and biological effects of genotoxic chemicals: Consensus report |
Título original |
Indications pour l'évaluation de l'exposition aux produits chimiques génotoxiques et de leurs effets biologiques: rapport commun [en francés] |
Información bibliográfica |
Office for Official Publications of the European Communities, Grand Duchy of Luxembourg, 2985 Luxembourg, 1988. 37p. 2 ref. Price: ECU 5.00. |
Resumen |
This document contains the report and conclusions of an international workshop held in Luxembourg in 1987. Nine types of biological monitoring methods are described: methods measuring the chemical or its metabolite in biological media; determination of mutagenic activity in biological material; cytogenetic observations on human somatic cells; detection of gene mutations in somatic cells; determination of protein or nucleic acid adducts; determination of markers of cell proliferation and transformation; determination of DNA repair; sperm assays; determination of nucleic acid damage by products in urine. It is concluded that none of the methods is able to assess exposure and estimate health risk at the individual level, although some methods are able to identify groups who are potentially at risk. Also available from the European Communities in the other official languages. |
Descriptores (primarios) |
substancias tóxicas; riesgos biológicos; efectos genéticos |
Descriptores (secundarios) |
anomalías genéticas; trastornos de la espermatogénesis; tests de mutagénesis; efectos biológicos; efectos cancerígenos; tumores; tests de exposición; exámenes citogenéticos; conferencia; dosificación en la orina; dosificación en medio biológico |
Tipo de documento |
E - Libros, informes, actas |
País / Estado o Provincia | Luxemburgo |
Tema(s) |
Sustancias tóxicas y peligrosas
|
Broad subject area(s) |
Riesgos químicos
|
Navegación por categoria(s) |
Antifertility and prenatal effects Biological hazards Genetic factors in reaction to exposures
|