ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento54910
Número CIS 90-1968
ISBN(s) 92-825-8909-9 (Eng); 92-825-8910-2 (fr)
Año 1988
Número de serie EUR 11659
Título Indicators for assessing exposure and biological effects of genotoxic chemicals: Consensus report
Título original Indications pour l'évaluation de l'exposition aux produits chimiques génotoxiques et de leurs effets biologiques: rapport commun [en francés]
Información bibliográfica Office for Official Publications of the European Communities, Grand Duchy of Luxembourg, 2985 Luxembourg, 1988. 37p. 2 ref. Price: ECU 5.00.
Resumen This document contains the report and conclusions of an international workshop held in Luxembourg in 1987. Nine types of biological monitoring methods are described: methods measuring the chemical or its metabolite in biological media; determination of mutagenic activity in biological material; cytogenetic observations on human somatic cells; detection of gene mutations in somatic cells; determination of protein or nucleic acid adducts; determination of markers of cell proliferation and transformation; determination of DNA repair; sperm assays; determination of nucleic acid damage by products in urine. It is concluded that none of the methods is able to assess exposure and estimate health risk at the individual level, although some methods are able to identify groups who are potentially at risk. Also available from the European Communities in the other official languages.
Descriptores (primarios) substancias tóxicas; riesgos biológicos; efectos genéticos
Descriptores (secundarios) anomalías genéticas; trastornos de la espermatogénesis; tests de mutagénesis; efectos biológicos; efectos cancerígenos; tumores; tests de exposición; exámenes citogenéticos; conferencia; dosificación en la orina; dosificación en medio biológico
Tipo de documento E - Libros, informes, actas
País / Estado o ProvinciaLuxemburgo
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Antifertility and prenatal effects
Biological hazards
Genetic factors in reaction to exposures