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Base de datos CISDOC

ID (ISN) del documento54443
Número CIS 90-1608
ISSN - Título de la serie 0002-8894 - American Industrial Hygiene Association Journal
Año 1989
Número de serie
Autor(es) Dreyfors J.M., Jones S.B., Sayed Y.
Título Hexamethylenetetramine: A review
Información bibliográfica Nov. 1989, Vol.50, No.11, p.579-585. 51 ref.
Resumen This review covers the available literature on hexamethylenetetramine (hexamine) with emphasis on its toxicology and epidemiology, its thermal decomposition and regulatory concerns related to its uses. Hexamine has many diverse industrial applications, particularly in the foundry, tyre and rubber, and phenoformaldehyde resins industries. Excessive exposure to solid hexamine or its vapour has been reported to cause dermatitis and respiratory allergies. Pure hexamine has been used as a food preservative and as an internal antiseptic in humans and animals. A WHO study in 1972 listed a temporary acceptance level of 5mg/kg body weight as an acceptable daily intake for man. Most animal studies have shown hexamine to be of very low genetic risk. Many thermal decomposition studies were initiated because of concern over the potential emission of toxic substances when hexamine was subjected to very high temperatures. Studies show that hexamine decomposition can be characterised by an increase in HCN and a decrease in NH3 emissions with increasing temperature, with release of HCN beginning at about 300°C. It is known that hexamine can decompose to form formaldehyde under acidic conditions.
Descriptores (primarios) hexametilenotetramina; industria del caucho; fundiciones; riesgos químicos; toxicología
Descriptores (secundarios) revisión bibliográfica; pirolisis; dermatitis; enfermedades respiratorias alérgicas; límites admisibles; investigaciones en el animal; productos de pirolisis
Tipo de documento D - Artículos periódicos
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Rubber industry
Heterocyclic compounds
Foundries, metalcasting and forging operations