| ID (ISN) del documento | 53087 |
| Número CIS |
90-203 |
| ISSN - Título de la serie |
0007-1072 - British Journal of Industrial Medicine |
| Año |
1988 |
| Número de serie |
|
| Autor(es) |
Jennings A.M., Wild G., Ward J.D., Milford Ward A. |
| Título |
Immunological abornalities 17 years after accidental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Información bibliográfica |
Oct. 1988, Vol.45, No.10, p.701-704. 38 ref. |
| Resumen |
Eighteen workers were reviewed 17yrs after accidental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin). Clinical assessment showed that they were in good health. A study of several biochemical and immunological parameters in these subjets and in 15 carefully matched controls showed no difference in serum concentrations of hepatic enzymes between the two groups. Antinuclear antibodies and immune complexes were detected significantly more frequently in the peripheral blood of workers exposed to dioxin. There was no significant difference in the number of T lymphocytes, B lymphocytes, and helper and suppressor T cell counts in peripheral blood, but the number of natural killer cells identified by the monoclonal antibody Leu-7 was significantly higher in workers exposed to dioxin. |
| Descriptores (primarios) |
industria química; valoración de la exposición; alteraciones de las inmunoglobulinas; tetraclorodibenzodioxina |
| Descriptores (secundarios) |
substancias tóxicas; exámenes médicos; estudio comparado; reacciones serológicas; pruebas bioquímicas |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Chemical industry
Exposure evaluation
Blood diseases
Heterocyclic compounds
|
