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Base de datos CISDOC

ID (ISN) del documento52980
Número CIS 89-1911
ISSN - Título de la serie 0007-1072 - British Journal of Industrial Medicine
Año 1989
Número de serie
Autor(es) De Klerk N.H., Cookson W.O.C., Musk A.W., Armstrong B.K., Glancy J.J.
Título Natural history of pleural thickening after exposure to crocidolite
Información bibliográfica July 1989, Vol.46, No.7, p.461-467. 27 ref. Illus.
Resumen Serial plain chest radiographs of 384 men who worked at the Wittenoom (Australia) crocidolite mine and mill between 1943 and 1966 and who applied for pneumoconiosis compensation between 1948 and 1982 have been examined independently by two trained observers for pleural disease using the 1980 ILO-UICC classification of radiographs to record width and extent of pleural disease. Radiographs covering follow up periods of from 2 to 38 years were examined (median number of films per subject was nine). The degree of crocidolite exposure was estimated from employment records and a survey of airborne fibre concentrations was performed in 1966. Diffuse pleural thickening extending for >50% of the lateral chest wall was the most common type recorded by both observers. Pleural plaques were not seen to progress beyond their initial thickness or extent. The rate of onset of thickening in this population increased continually from the time of first exposure and also increased slightly with age. There was evidence that the level of total cumulative exposure to crocidolite increased the rate of onset of pleural thickening in the period between 5-15yr after first exposure. The relative rate of progression decreased slowly with time from first signs of thickening, with no progression >15yr after onset.
Descriptores (primarios) paquipleuritis; crocidolita; clasificaciones radiológicas; radiografía de tórax; minas de amianto
Descriptores (secundarios) Australia; evolución de la enfermedad; valoración de la exposición; edad; enfermedades pleurales
Tipo de documento D - Artículos periódicos
Tema(s) Polvos, aerosoles
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Mining and quarrying
Diseases of the respiratory system (except for pneumoconiosis & similar)
Asbestos