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Base de datos CISDOC

ID (ISN) del documento52974
Número CIS 89-1939
ISSN - Título de la serie 0007-1072 - British Journal of Industrial Medicine
Año 1989
Número de serie
Autor(es) Araki S., Aono H.
Título Effect of water restriction and water loading on daily urinary excretion of heavy metals and organic substances in metal workers
Información bibliográfica June 1989, Vol.46, No.6, p.389-392. 18 ref. Illus.
Resumen The effects of urinary volume on daily urinary excretion of seven heavy metals and four organic substances were examined in relation to the changes in their plasma and erythrocyte concentrations and urinary creatinine excretion in 19 metal workers. The examination was conducted under the conditions of water restriction and loading for six days. The major findings were as follows: (1) urinary excretion of all heavy meatals and organic substances except mercury, together with creatinine excretion, significantly decreased under conditions of water restriction whereas under conditions of water loading their excretion increased significantly; (2) daily variations in urinary excreton of lead, cadmium, chromium, copper, hippuric acid, δ-aminolaevulinic acid, and coproporphyrin did not differ significantly from the variation in urinary excretion of creatinine. It is suggested that glomerular filtration is the major factor determining renal excretory mechanisms of the substances examined.
Descriptores (primarios) compuestos orgánicos; metales; fundiciones; privación de agua; excreción urinaria
Descriptores (secundarios) valoración estadística; estudio comparado; excreción de creatinina; tests de exposición
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Foundries, metalcasting and forging operations
Inorganic substances