| ID (ISN) del documento | 52423 |
| Número CIS |
89-1580 |
| ISSN - Título de la serie |
Gigiena truda i professional'nye zabolevanija |
| Año |
1987 |
| Número de serie |
|
| Autor(es) |
Šmidt P., Ivanov N.G. |
| Título |
Methodological approaches to the assessment of short-term exposure to industrial chemicals with hepatotoxic properties |
| Título original |
Metodočeskie podhody k ocenke gepatotropnogo dejstvija promyšlennyh veščestv pri kratkosročnom vozdejstvii [en ruso] |
| Información bibliográfica |
Dec. 1987, No.12, p.33-36. Illus. 8 ref. |
| Resumen |
Animal experiments carried out to investigate changes in liver function as a result of short-term exposure to known hepatotoxic chemicals (carbon tetrachloride, allyl alcohol, styrene) and to new industrial chemical compounds (diallyl phthalate, diaminodiphenylmethane etc.) showed the need for standardisation of experimental conditions for determination of the threshold of acute action of toxic chemicals on liver function for the purposes of hygienic standardisation. A set of compulsory and additional tests for detecting hepatotoxic effects of occupational poisons under conditions of short-term exposure is recommended. |
| Descriptores (primarios) |
metileno-4,4' dianilina; alcohol alílico; efectos hepatotóxicos; normalización; estireno; ftalato de dialilo; tetracloruro de carbono |
| Descriptores (secundarios) |
cloroformo; tetracloro-1,1,2,2 etano; isoftalato de dialilo; exposición de corta duración; substancias tóxicas; investigaciones en el animal; perturbaciones metabólicas |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Alcohols
Aromatic amines
Phthalates
Halogenated hydrocarbons
Aromatic hydrocarbons
Esters and salts
|
