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Base de datos CISDOC

ID (ISN) del documento48882
Número CIS 88-206
ISSN - Título de la serie 0003-4878 - Annals of Occupational Hygiene
Año 1986
Número de serie
Autor(es) Seniori Costantini A., Paci E., Scala D., Cariaggi P., Cipparrone G., Confortini M., Maddau C., Butt R., Dolara P., Salvadori M., Caderni G.
Título Monitoring of carcinogenic risks in tannery workers by means of desquamative lung and bladder cytology and urinary mutagenicity
Información bibliográfica 1986, Vol.31, No.1, p.21-30. Illus. 18 ref.
Resumen Proportional mortality data on a cohort of tannery workers showed an increased risk of lung cancer, oesophageal cancer, sarcomas and leukaemias. From a cohort of workers and controls in the same area, data were obtained on urinary mutagenic activity using Salmonella typhimurium TA1538 and TA100 as tester strains, with and without metabolic activation. The mutagenic activity of the urine of tanning workers did not differ from that of clerical workers. Bladder desquamative cytology did not show any difference between clerical controls and workers. Pulmonary cytology specimens were normal or showed cellular atypical metaplasia. No cases with atypical cells or obvious neoplastic changes were found. The relative risk of pathological lung cytology was higher in chemical refining than in mechanical refining and tanning.
Descriptores (primarios) efectos mutágenos; substancias cancerígenas; cáncer de pulmón; citología del esputo; curtiduría; citología urinaria; valoración de la exposición
Descriptores (secundarios) encuesta epidemiológica; mortalidad
Tipo de documento D - Artículos periódicos
Tema(s) Cueros y pieles, calzados
Broad subject area(s) Industrias y ocupaciones
Navegación por categoria(s) Antifertility and prenatal effects
Diseases of the respiratory system (except for pneumoconiosis & similar)
Footwear, leather and fur industry
Genetic factors in reaction to exposures
Exposure evaluation