| ID (ISN) del documento | 48772 |
| Número CIS |
87-1423 |
| ISBN(s) |
91-7464-294-4 |
| Año |
1986 |
| Número de serie |
Arbete och Hälsa 1986:8
|
| Autor(es) |
Swensson A. |
| Título |
Nordic Expert Group for Documentation of Threshold Limit Values - 65. Allyl alcohol |
| Título original |
Nordiska expertgruppen för gränsvärdesdokumentation - 65. Allylalkohol [en sueco] |
| Información bibliográfica |
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1986. 38p. Illus. 81 ref. |
| Resumen |
A critical review of the literature relevant to discussions for an exposure limit is presented. In man the earliest symptom of exposure to allyl alcohol is irritation of the mucous membranes. Damage to internal organs has not been registered. In animal experiments the liver was found to be the most severely damaged organ, while damage to other organs was slight. In long-term experiments a certain adaptation was demonstrated in that the liver when damaged may heal in spite of continued exposure. There is no information on teratogenicity or carcinogenicity. The metabolite glycidaldehyde may have slight carcinogenic properties. Allyl alcohol is mutagenic in the Ames test. A threshold limit value should prevent mucous membrane irritation. |
| Descriptores (primarios) |
efectos mutágenos; valores umbrales; determinación de los límites de la exposición; alcohol alílico; efectos hepatotóxicos; substancias irritantes |
| Descriptores (secundarios) |
países nórdicos; documentación de base; investigaciones en el animal |
| Tipo de documento |
F - Notas informativas, directrices prácticas, normas |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Alcohols
Genetic factors in reaction to exposures
Occupational exposure limits
Antifertility and prenatal effects
|
