| ID (ISN) del documento | 42438 |
| Número CIS |
84-1316 |
| ISBN(s) |
91-7464-151-4 |
| Año |
1982 |
| Número de serie |
Arbete och hälsa 1982:32
|
| Autor(es) |
Bellander T., Hagmar L. |
| Título |
Morpholine |
| Título original |
Morfolin [en sueco] |
| Información bibliográfica |
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1982. 32p. 92 ref. |
| Resumen |
Criteria document based on literature data. Morpholine is a cyclic secondary amine with corrosive and irritant action. It is readily taken up by the skin, and is excreted in the urine unchanged. High concentrations are required to produce effects in toxicological experiments. Morpholine is not mutagenic, but it is readily converted to the mutagenic N-nitrosomorpholine in the presence of nitrites in vitro and in vivo. Evaluation of morpholine exposure must thus take account of exposure to potential nitrosating agents such as nitrites or nitrous oxide. |
| Descriptores (primarios) |
n-nitrosomorfolina; morfolina; substancias nocivas; toxicología |
| Descriptores (secundarios) |
revisión bibliográfica; mutágenos; substancias corrosivas; efectos nefrotóxicos; substancias cancerígenas; efectos hepatotóxicos; substancias irritantes |
| Tipo de documento |
E - Libros, informes, actas |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Heterocyclic compounds
|
