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ID (ISN) del documento41894
Número CIS 84-834
ISSN - Título de la serie 0340-0131 - International Archives of Occupational and Environmental Health
Año 1983
Número de serie
Autor(es) Franchini I., Cavatorta A., Falzoi M., Lucertini S., Mutti A.
Título Early indicators of renal damage in workers exposed to organic solvents
Información bibliográfica 1983, Vol.52, No.1, p.1-9. Illus. 33 ref.
Resumen 438 workers from 11 factories and 29 dry-cleaning shops were studied: 57 exposed to perchloroethylene; 118 painters exposed to benzene homologues at 5 metalworking factories; 51 exposed to styrene vapours in glass-fibre-reinforced plastics boat and silo manufacture; and 212 workers exposed to C5-C7 alkanes; also 2 control groups (80 and 81 workers). Renal function was investigated by determination of total proteinuria, albuminuria and urinary muramidase and β-glucuronidase. There was little evidence of renal damage due to solvent exposure. Total proteinuria was significantly increased in workers exposed to alkanes and to styrene, but this finding did not correspond to other changes. Any renal damage appeared to be mild and tubular rather than glomerular. The methods are intended as screening procedures and not as a substitute for clinical diagnosis of renal diseases.
Descriptores (primarios) diagnostico precoz; lesiones renales; tests de exposición; disolventes orgánicos; limpieza en seco
Descriptores (secundarios) tetracloroetileno; tolueno; estireno; proteinuria; xileno; estudio comparado; transformación de materias plásticas; hidrocarburos alicíclicos; hidrocarburos alifáticos; dosificación en la orina; transformación de metales
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Laundries and dry cleaning
Biological monitoring
Diseases of the kidney and the urinary system