| ID (ISN) del documento | 41390 |
| Número CIS |
84-470 |
| ISSN - Título de la serie |
0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku |
| Año |
1983 |
| Número de serie |
|
| Autor(es) |
Misumi J., Koyama W., Miura H. |
| Título |
Two cases of "green-tobacco sickness" in tobacco harvesters and absorption of nicotine through the skin in the rat |
| Información bibliográfica |
1983, Vol.25, No.1, p.3-9. Illus. 11 ref. |
| Resumen |
These are the first cases reported in Japan, occurring in both non-smokers and non-drinkers. Symptoms are dizziness, nausea and generalised weakness, and develop after exposure to wet raw tobacco leaves, probably as a result of absorption of nicotine through the skin. Studies in rats showed the minimum toxic dose of nicotine through the skin to be 21mg/kg body weight. The toxic dose in humans might be <1.96mg/kg body weight. |
| Descriptores (primarios) |
nicotina; cultivo de tabaco; enfermedad del tabaco verde |
| Descriptores (secundarios) |
Japón; investigaciones en el animal; absorción cutánea; estudio de caso |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Heterocyclic compounds
Agricultura
|
