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ID (ISN) del documento40274
Número CIS 83-1447
Año 1983
Número de serie
Autor(es) Steunou M.T.
Título Personnel in genetic engineering laboratories: an attempt to evaluate occupational hazards due to antibiotic resistance in E. coli K12
Título original Personnel des laboratoires de génie génétique: essai d'évaluation des risques professionnels à partir de l'antibiorésistance liée à E. coli K12 [en francés]
Información bibliográfica Université René Descartes, Faculté de médecine Cochin Port-Royal, Paris, France, 1983. 103p. 66 ref.
Resumen This medical school thesis assesses the occupational hazards to which the personnel of genetic engineering laboratories are exposed. A description of genetic processes in bacteria and their application in genetic engineering is followed by a description of the bacterium Escherichia coli (E. coli), especially E. coli K12, and its pathogenic potential. Safety standards applicable to genetic engineering laboratories in the USA and France are reviewed. The skins, throats and stools of personnel at 3 workstations in a genetic engineering laboratory were examined for the presence of multiply antibiotic-resistant E. coli K12. Technicians performing conjugation and centrifugation showed some cutaneous contamination, but no contamination of the gastrointestinal tract was found. Nonetheless, special medical surveillance of the personnel of genetic engineering laboratories, to guard against presently unidentified hazards, is necessary.
Descriptores (primarios) laboratorios; trabajos de laboratorio; institutos de investigación; ingeniería genética; bacterias patógenas
Descriptores (secundarios) Francia; enfermedades infecciosas; tesis; vigilancia médica; riesgos biológicos; legislación; prevención del contagio
Tipo de documento E - Libros, informes, actas
Tema(s) Cemercio, servicios, oficinas
Broad subject area(s)
Navegación por categoria(s) Bacterial and parasitic diseases