ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento38526
Número CIS 82-1698
ISSN - Título de la serie 0019-8366 - Industrial Health
Año 1981
Número de serie
Autor(es) Suzuki Y., Toda K., Koike S., Yoshikawa H.
Título Cadmium, copper and zinc in the urine of welders using cadmium-containing silver solder
Información bibliográfica 1981, Vol.19, No.4, p.223-230. Illus. 17 ref.
Resumen Urine samples from 12 male welders aged 20 to 50 years who had been engaged in work with cadmium-containing silver solder for 3-23 years were analysed for cadmium (Cd), copper (Cu), and zinc (Zn) and compared with samples from 5 controls. Mean concentration values of Cd, Cu, and Zn for welders were 26, 2.4 and 2.6 times those of controls. A linear relation was found between urine concentrations of Cd, and both Cu and Zn. In chromatographic analyses of samples from 2 welders suspected of suffering from Cd-induced renal injury, the metallothionein fraction contained Cd and Cu but not Zn, and the Cu content of this fraction was much greater than the Cd content. The Cd and Cu in this fraction represented 6 and 10% of totals; the remaining Cd and Cu were recovered from high molecular weight protein and low molecular weight non-protein fractions. Urinary Zn was present in both of these fractions. Cd accumulation affects the excretion of Cu and Zn in urine, and urinary excretion of metallothionein containing Cd and Cu may be involved in Cd-induced renal injury.
Descriptores (primarios) cobre; zinc; cadmio; estanado; efectos nefrotóxicos; lesiones renales
Descriptores (secundarios) pruebas de las funciones renales; dosificación en la orina; vigilancia de la orina
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Diseases of the kidney and the urinary system
Inorganic substances
Welding and cutting
Copper and compounds
Cadmium and compounds