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Base de datos CISDOC

ID (ISN) del documento38453
Número CIS 82-1677
ISSN - Título de la serie 0019-8366 - Industrial Health
Año 1982
Número de serie
Autor(es) Nomiyama K., Nomiyama H., Yotoriyama M.
Título Low-molecular-weight proteins in urine from rabbits given nephrotoxic compounds
Información bibliográfica 1982, Vol.20, No.1, p.1-10. Illus. 25 ref.
Resumen Rabbits were given 0.5mg cadmium (Cd)/kg by subcutaneous injection 6 times a week for 32 weeks. The main protein component in the urine of these animals had a molecular weight (MW) of ≥67,000 suggesting tubular and glomerular dysfunction. Low MW proteins were found, in addition, in the urine of animals given a single injection of uranium (U), chromium (Cr), or mercury (Hg). The MW distribution of proteins in the urine of these animals was very similar to that of Cd-treated rabbits. Low MW tubular reabsorption of phosphorus was >80%.
Descriptores (primarios) mercurio; uranio; toxicología; cromo; efectos nefrotóxicos; cadmio; proteinuria
Descriptores (secundarios) investigaciones en el animal; disfunción renal
Tipo de documento D - Artículos periódicos
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Diseases of the kidney and the urinary system
Mercury and compounds
Cadmium and compounds
Inorganic substances