| ID (ISN) del documento | 33338 |
| Número CIS |
80-734 |
| ISSN - Título de la serie |
0003-4878 - Annals of Occupational Hygiene |
| Año |
1979 |
| Número de serie |
|
| Autor(es) |
Greig J.B. |
| Título |
The toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin and its structural analogues. |
| Información bibliográfica |
1979, Vol.22, No.4, p.411-420. 71 ref. |
| Resumen |
The signs and symptoms (chloracne, liver damage, oedema, cardiovascular disorders) of TCDD poisoning in humans are corelated with experimental animal models and the effects of body distribution and metabolism on the toxicity of TCDD are discussed. The activity of TCDD analogues in relation to molecular shape and size is discussed and a case of poisoning is presented which might be due to chlorinated xanthenes, steric analogues of TCDD which have not yet been implicated in chloracne outbreaks. |
| Descriptores (primarios) |
tetraclorodibenzodioxina; acné clórico; toxicología; dioxinas |
| Descriptores (secundarios) |
revisión bibliográfica; envenenamiento agudo; metabolización; investigaciones en el animal; xantenos clorados; bencil-2 cloro-4 fenol; estructura molecular |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Heterocyclic compounds
Toxicology
Skin diseases
|
