| ID (ISN) del documento | 29438 |
| Número CIS |
78-1083 |
| ISSN - Título de la serie |
0340-0131 - International Archives of Occupational and Environmental Health |
| Año |
1977 |
| Número de serie |
|
| Autor(es) |
Hansén L., Kjellström T., Vesterberg O. |
| Título |
Evaluation of different urinary proteins excreted after occupational Cd exposure. |
| Información bibliográfica |
22 Dec. 1977, Vol.40, No.4, p.273-282. Illus. 22 ref. |
| Resumen |
55 male workers at an alkaline battery factory were examined for renal effects after several years' exposure to cadmium. Total urinary protein was determined using a biuret method. To separate the individual proteins, isoelectric focussing was done in flat beds of polyacrylamide gel. The proteins were then stained and evaluated by densimetry. Duration of exposure was taken as a measure of the dose. There was a dose-effect relation between Cd and some urinary proteins. The most pronounced relative increases occurred in the zones containing albumin and β2-microglobulin. Albumin showed the largest quantitative increase. The method appears suitable for evaluating the renal effects of cadmium. |
| Descriptores (primarios) |
proteinuria; fabricación de pilas y acumuladores; cadmio; tests de exposición; efectos nefrotóxicos |
| Descriptores (secundarios) |
valoración de la exposición; descripción del procedimiento; citología urinaria; relación dosis-respuesta |
| Tipo de documento |
- |
| Tema(s) |
Patología profesional
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Inorganic substances
Cadmium and compounds
Biological monitoring
Diseases of the kidney and the urinary system
Manufacturing of electrical appliances and equipment
|
